Omega-3 Fatty Acids and Metabolic Health: What You Need to Know

We all share a common desire for vibrancy, to create a healthier, more vibrant version of ourselves. As we navigate the labyrinth of nutrition and wellness advice that’s out there, it’s important to pay attention to the nutrients that can truly make a difference in our journey toward optimal health. 

Among these, omega-3 fatty acids really stand out! These essential fats, found abundantly in certain foods or available as a supplement, offer a myriad of benefits that extend beyond mere physical well-being. They hold the key to nourishing our bodies from within, fostering resilience, and promoting balance in our metabolic functions.

Before we dive into the complexities of omega-3s and metabolic health, let’s take a moment to understand the basics. Omega-3 fatty acids are a family of polyunsaturated fats, with three primary members stealing the spotlight:

  • Alpha-linolenic acid (ALA)
  • Eicosapentaenoic acid (EPA)
  • And docosahexaenoic acid (DHA)

The significance of Omega-3 fatty acids in promoting overall health cannot be overstated. These healthy fats are renowned for their anti-inflammatory properties, aiding in the prevention and management of chronic diseases. Moreover, recent research illuminates a compelling nexus: the profound impact of omega-3s on metabolic health.

The Role of Omega-3 Fatty Acids in Metabolic Health

A growing body of research underscores the profound impact of omega-3s on metabolic well-being. From large-scale observational studies highlighting the association between omega-3 intake and improved insulin sensitivity, to controlled clinical trials demonstrating the potential to reduce inflammation and metabolic syndrome markers, the scientific landscape is rich with findings supporting the integral role of omega-3s in fostering metabolic health.

First of all, these essential fatty acids have been shown to enhance insulin function, helping cells efficiently respond to this hormone crucial for blood sugar balance. By promoting insulin sensitivity, omega-3s contribute to the maintenance of balanced blood sugar levels, a crucial factor in the intricate dance of metabolic regulation. (1)

Beyond their influence on insulin, omega-3 fatty acids wield a powerful effect on blood sugar levels themselves. Studies suggest that incorporating omega-3-rich foods or supplements into your diet may play a role in stabilizing blood glucose, offering a promising avenue for those navigating the complexities of blood sugar management.

But the connection between omega-3s and metabolic health doesn’t end there! Chronic inflammation is a known driver of metabolic disorders, and omega-3 fatty acids, with their potent anti-inflammatory properties, emerge as natural defenders to keep inflammation at bay. By modulating inflammatory pathways, these fats may contribute to mitigating the risks associated with metabolic syndrome, a cluster of conditions that includes:

  • Elevated blood pressure
  • High blood sugar
  • Excess abdominal fat
  • And abnormal cholesterol levels

Omega-3s and Weight Management

Another surprising aspect of omega-3s is their impact on fat metabolism. They have been shown to enhance the body’s ability to burn fat for energy, a process known as lipid oxidation. This not only aids in the body’s ability to shed unwanted pounds but also supports the preservation of lean muscle mass, a crucial factor in maintaining a healthy metabolism during weight loss efforts.

Studies suggest that omega-3 fatty acids may also contribute to reducing the size and number of fat cells, particularly in abdominal areas associated with visceral fat accumulation. This visceral fat, known to be metabolically active and linked to various health risks, becomes a targeted focus in the endeavor for effective weight management. (2)

Use the tips below to help incorporate omega-3s into a successful weight management program:

  • Eat one serving of fatty fish per day (my favorite is a can of salmon or sardines in my salad)
  • Add flaxseeds to your breakfast smoothie / oats
  • Use omega-3 enriched eggs at breakfast or in recipes 
  • Use flax oil instead of canola oil in homemade salad dressings

Omega-3 Fatty Acids and Cardiovascular Health

The positive impact of omega-3 fatty acids on metabolic markers, such as improved insulin sensitivity and regulated blood sugar levels, creates a ripple effect that extends to cardiovascular health. (3)

By fostering a balanced metabolic environment, omega-3s contribute to the prevention of risk factors associated with cardiovascular diseases, such as hypertension and dyslipidemia.

The contribution of omega-3s to a healthy cardiovascular system is manifested in various ways. One key aspect is their ability to regulate lipid profiles. Omega-3 fatty acids, particularly EPA and DHA, have been shown to lower levels of triglycerides, reduce inflammation, and improve the ratio of high-density lipoprotein (HDL) to low-density lipoprotein (LDL) cholesterol. This lipid-modulating effect plays a pivotal role in reducing the risk of atherosclerosis and coronary artery disease.

Furthermore, omega-3s exhibit anti-inflammatory properties that extend to the cardiovascular system. Chronic inflammation is a known contributor to the development and progression of cardiovascular diseases. By mitigating inflammation, omega-3 fatty acids act as natural guardians, safeguarding the delicate balance of the cardiovascular ecosystem.

Which Foods are High in Omega 3?

When it comes to including omega-3s in your diet, you have two options. One is through food (animal sources are often considered better than plant sources due to the specific types of omega-3s they provide and their bioavailability) and the other is through supplementation. 

Foods rich in omega-3 fatty acids:

Animal Sources: Fatty Fish: Salmon, herring, mackerel, trout, sardines. Other: Omega-3 enriched Eggs

  • Pros: Rich in EPA and DHA, the most bioavailable forms of omega-3s.
  • Cons: Environmental concerns, Risk of heavy metal contamination (click here to see how this can be mitigated)

Plant Sources: Flaxseeds, Chia Seeds, Walnuts, Hemp Seeds.

  • Pros: Rich in ALA, a precursor to EPA and DHA.
  • Cons: Conversion of ALA to EPA and DHA in the body is poor; only about 3-5% is converted to EPA/DHA, but research supports their ability to reduce some inflammatory markers.

For individuals with limited access to omega-3-rich foods or those requiring higher doses for specific health conditions, supplementation may be beneficial.

Choose reputable brands that provide third-party testing for purity and potency, and always consult with a healthcare provider to determine appropriate dosage and form (fish oil, algae oil) based on individual needs and health status.

While omega-3 fatty acids offer a plethora of health benefits, maintaining a balanced ratio of omega-3 to omega-6 fatty acids is essential. In Western diets, omega-6 fatty acids, found abundantly in vegetable oils and processed foods, typically overshadow omega-3s at levels as high as 20:1, leading to an imbalance associated with inflammation and chronic diseases. It has been suggested that a ratio of 2 or 3:1 is a more favorable omega 6:3 ratio. (5)

To strike a harmonious balance:

  • Increase consumption of omega-3-rich foods.
  • Reduce intake of processed foods high in omega-6 fatty acids.
  • Choose oils with a favorable omega-3 to omega-6 ratio, such as olive oil and flax oil (4). To preserve the integrity of the omega-3 in these oils, do not use them in cooking.
  • Aim for a balanced ratio of omega-3 to omega-6 fatty acids in your diet to support overall health and well-being.


From their role in metabolic health to their influence on cardiovascular well-being and even aiding in weight management, omega-3s stand as versatile and potent contributors to a healthier, more vibrant life.

However, in your quest for optimal health, it’s crucial to recognize the uniqueness of individual needs. A personalized approach is the key to unlocking the full potential of omega-3s for you. Therefore, we encourage you to seek the guidance of healthcare professionals, who can provide personalized advice based on your specific health status and goals.

As you embark on this path towards well-being, consider taking that extra step by scheduling a discovery call! I’m here to offer support, answer your questions, and help you tailor a plan that aligns with your unique needs!


  1. Howe, Peter, and Jon Buckley. “Metabolic health benefits of long-chain omega-3 polyunsaturated fatty acids.” Military medicine vol. 179,11 Suppl (2014): 138-43. doi:10.7205/MILMED-D-14-00154 PMID: 25373098
  2. Buckley, Jonathan D, and Peter R C Howe. “Long-chain omega-3 polyunsaturated fatty acids may be beneficial for reducing obesity-a review.” Nutrients vol. 2,12 (2010): 1212-1230. doi:10.3390/nu2121212 PMID: 22254005
  3. Jain, A P et al. “Omega-3 fatty acids and cardiovascular disease.” European review for medical and pharmacological sciences vol. 19,3 (2015): 441-5. PMID: 25720716
  4. Tamtaji, Omid Reza et al. “Effects of flaxseed oil supplementation on biomarkers of inflammation and oxidative stress in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials.” Clinical nutrition ESPEN vol. 40 (2020): 27-33. doi:10.1016/j.clnesp.2020.09.017 PMID: 33184549
  5. Simopoulos, Artemis P. “The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases.” Experimental biology and medicine (Maywood, N.J.) vol. 233,6 (2008): 674-88. doi:10.3181/0711-MR-311 PMID: 18408140
Print Friendly, PDF & Email

Leave a Comment

Your email address will not be published. Required fields are marked *